5th Workshop of Structural Biology in the Helmholtz Association

from Tuesday, 17 December 2019 (12:00) to Wednesday, 18 December 2019 (23:30)
German Cancer Research Center / Communication Center (Lecture Hall)

        : Sessions
    /     : Talks
        : Breaks
17 Dec 2019
18 Dec 2019
AM
09:00
Integrative Structural Biology: Molecular Mechanism (until 11:00) (Lecture Hall)
09:00 Sulfide protects [FeFe] hydrogenase from oxygen - Ingrid Span (Heinrich-Heine-Universität Düsseldorf)   (Lecture Hall)
09:20 Understanding the function of the dynamin molecular motor through a synthesis of structural and kinetic data - Jeff Noel (MDC)   (Lecture Hall)
09:40 Structural snapshots along a factor-dependent transcription termination pathway - Nelly Said (Freie Universität Berlin)   (Lecture Hall)
10:00 Structure and Function of the Phospholipase PlaB from Legionella pneumophila - Maurice Diwo (Helmholtz Centre for Infection Research - SFPR)   (Lecture Hall)
10:20 Structural basis for Microtubule nucleation by the gamma-Tubulin Ring Complex - Mr Erik Zupa (Zentrum fur Molekulare Biologie)   (Lecture Hall)
10:40 Enzyme watching: a molecular motor in action - Anne Schuetz (TU Munich)   (Lecture Hall)
11:00 --- Coffee Break ---
11:30
integrative Structural Biology: New Approaches (until 13:10) (Lecture Hall)
11:30 HIGH OUTPUT SERIAL CRYSTALLOGRAPHY TO IMAGE THE STRUCTURE AND DYNAMICS OF BIOLOGICAL MOLECULES - Dr Dominik Oberthuer (Center for Free-Electron Laser Science CFEL, Deutsches Elektronen Synchrotron DESY, Hamburg, Germany)   (Lecture Hall)
11:50 High-pressure X-ray crystallography of macromolecules - Julia Lieske   (Lecture Hall)
12:10 High-energy, low-background protein diffraction - Dr Sebastian Guenther (DESY)   (Lecture Hall)
12:30 Structural insights into membrane and cellular systems - Manuel Etzkorn   (Lecture Hall)
12:50 Structural and functional mechanism of alternative splicing regulation of the immune cell protease MALT1 - Dr Alisha Jones (Helmholtz Zentrum Muenchen)   (Lecture Hall)
PM
12:00 --- Arrival and Reception ---
13:00
Overviews: Integrative Structural Biology at Helmholtz (until 15:00) (Lecture Hall)
13:00 Overview & Perspectives - Michael Sattler   (Lecture Hall)
13:10 P11 at PETRA III: A Versatile Beamline for High-Throughput and Serial Crystallography - Dr Anja Burkhardt (DESY)   (Lecture Hall)
13:30 Crystallographic fragment-screening at the HZB - Manfred Weiss (Helmholtz Zentrum Berlin)   (Lecture Hall)
13:50 Cryo-EM - a status update and future developments - Prof. CARSTEN SACHSE   (Lecture Hall)
14:10 Helmholtz-PSPF: Protein Sample Production for Integrative Structural Biology - Dr Johannes van den Heuvel (Helmholtz Zentrum für Infektionsforschung)   (Lecture Hall)
14:30 TBA - Michael Kolbe   (Lecture Hall)
15:00 --- Coffee Break ---
15:30
Integrative Structural Biology: Innovative Therapeutics (until 17:30) (Lecture Hall)
15:30 Novel Vaccines from a Parasite Coat - Dr Erec Stebbins (Deutsches Krebsforschungszentrum)   (Lecture Hall)
15:50 Human cis-aconitate decarboxylase: Structural basis of activity-modulating mutations - Dr Konrad Büssow (Helmholtz Centre for Infection Research)   (Lecture Hall)
16:10 Structural variation of norovirus vaccine candidate GII.4c virus like particles - Jessica Michelle Devant (Deutsches Krebsforschungszentrum)   (Lecture Hall)
16:30 Fighting beta-lactamase activity using a combination of known and novel small molecule inhibitors. - Dr Krzysztof Zak (Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany)   (Lecture Hall)
16:50 Focused Library Generator: case of Mdmx inhibitors - Zhonghua Xia   (Lecture Hall)
17:10 Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts - Dr Timo Strohäker (German Center for Neurodegenerative Diseases (DZNE))   (Lecture Hall)
17:30
Poster session (until 19:20) (Communication center)
17:50 --- CPA Meeting Group Leaders ---
19:20 --- Dinner ---