WELCOME to the Günther Schütz Symposium
Prof. Dr. Günther Schütz is among the giants in cell and molecular biology, his scientific work contributed very significantly to the function and molecular regulation of hormone receptors and gene transcriptional regulations. Most importantly, he cultivated several generations of scientists who are active academic leaders all around the world. To celebrate his life and work, we invite you to participate in the Günther Schütz Symposium in Heidelberg. Several aspects of his grand legacy will be highlighted and discussed on this symposium.
Günther Schütz passed away on May 28, 2020, at the age of 80. Günther Schütz was born in Bad Schwalbach (Germany) in 1940. He studied medicine in Frankfurt, Bern and Giessen and obtained his MD at the Institute of Physiological Chemistry of Marburg University. In 1969, he went to New York’s Columbia University as a postdoctoral researcher in Philip Feigelson’s lab and most likely there he was trapped by the hormonal regulation of gene expression, particularly by glucocorticoids. In 1975, he returned to Germany and led a working group at the Max Planck Institute for Molecular Genetics in Berlin until 1980. In that year, he was appointed head of the division of “Molecular Biology of the Cell I” at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg, where he stayed until his definitive retirement in 2015. In 1988, he received the most prestigious research award in Germany, the Leibniz Prize. Since 2008 he had been selected as the first Helmholtz Professor after reaching his retirement age.
We are all committed that this memorial Symposium will be an exciting event to discuss the latest developments in biomedical research, which we believe is the best way to remember Günther Schütz.
We are looking forward to your registration !
Registration will be open until Wednesday, 17th of May 2022, 23:59 CEST
The Organizing Committee
CHAIRS / PROGRAM COMMITTEE
Thursday 19 May 2022
Session 1: Welcome, honours and keynote speakers
Chairs: Hai-kun Liu and Siegfried Ruppert
09:00-10:30 Michael Boutros (Deputy Director, German Cancer Research Center)
Otmar D. Wiestler (President, Helmholtz Association of German Research Centres)
Harald zur Hausen (Prof. em., German Cancer Research Center)
Siegrun Korth- Schütz and family delegates
Werner W. Franke (Prof. em., German Cancer Research Center)
Bernd Groner (Prof. em Georg Speyer Haus, Institute for Tumor Biology and Experimental Therapy Goethe University, Frankfurt am Main, Germany) From New York to Berlin in 1975
Peter Becker (Biomedical Center, Ludwig-Maximilian-University, Munich, Germany) Lab life in the mid?1980s: a PhD perspective
10:30-11:00 Coffee/Tea break
Session 2: Nuclear Hormone Receptors and Chromatin
Chair: Nancy Hynes
11:00-11:20 Jan Tuckermann (Institute of Comparative Molecular Endocrinology (CME) University of Ulm, Germany) Always good for surprises: The GR
11:20-11:40 Timothy Cole (Department of Biochemistry & Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne) Dissecting actions of the adrenal steroid nuclear receptors via conditional mutagenesis
11:40-12:00 Andreas Schedl (Université Cote d'Azur, Inserm, CNRS, iBV, Nice, France) Stem cells, sex and signalling: How to ensure functional zonation and tissue renewal of the adrenal cortex
12:00-12:20 Maja Vujic Spasic (Institute of Comparative Molecular Endocrinology, University Ulm, Ulm, Germany) Cross-talk between glucocorticoids and iron metabolism
Session 3: Initiatives in Functional Enquiry
Chair: Hans Weiher
13:40-14:00 Peter B. Becker (Biomedical Center, Division of Molecular Biology, Faculty of Medicine, Ludwig Maximilian University, Munich, Germany) DNaseI-hypersensitivity – 35 years on
14:00-14:20 A. Francis Stewart (Center for Molecular and Cellular Bioengineering, TU Dresden, Germany) Conditional mutagenesis to investigate epigenetic regulation
14:20-14:40 Gavin Kelsey (Epigenetics Programme, The Babraham Institute, Cambridge, United Kingdom) Epigenetic inheritance: understanding epigenetic programming in the germline
14:40-15:00 Lluis Montoliu (National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain) From mice to humans: from tyrosinase to albinism
15:00-15:20 Patrick Matthias (Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland) Role of the deacetylase HDAC6 and unanchored ubiquitin chains in viral infection
15:20-15:40 Coffee/Tea break
Session 4: Brain 1
Chair: A. Francis Stewart
15:40- 16:00 A. Paula Monaghan (Biomedical Sciences, UMKC School of Medicine, Kansas City, USA; Zoom – 08.40 Kansas City time) Deciphering the impact of glucocorticoid exposure in the neonatal brain
16.00-16.20 Stavros Taraviras (Department of Physiology, Medical School, University of Patras, Greece) Fate commmitment decisions of neural stem cells
16.20-16.40 François Tronche (CNRS UMR8246, UPMC UM119, INSERM UMRS1130, Institut de Biologie, Sorbonne Université, Paris, France) Stress, chromatin remodelers and social behaviour
16:40-17:00 Christoph Kellendonk (Departments of Psychiatry and Molecular Pharmacology & Therapeutics, New York State Psychiatric Institute, Columbia University, New York, USA) Thalamo-cortical interactions in cognition
17:00 - 17:20 Witold Konopka (Neurobiology Center, Nencki Institute of Experimental Biology, Warsaw, Poland) MicroRNAs in brain body metabolic games
19:00 Dinner at Restaurant ROSSINI (Neuenheim)
Master of ceremony: Wolfgang Schmid
Speakers during dinner – Albrecht Sippel et al, volunteers welcome (beamer available).
Friday 20 May 2022
Session 5: Brain 2
Chair: Rosanna Parlato
09:30-09:50 Beat Lutz (Leibniz Institute for Resilience Research (LIR) and Institute of Physiological Chemistry, University Medical Center (UMC), Mainz, Germany) The fascinating spheres of (endo)cannabinoid signalling
09:50-10:10 David Engblom (Linköping University, Linköping, Sweden) Feeling sick: molecular mechanisms
10:10-10:30 Rainer Spanagel (Institute of Psychopharmacology, Central Institute of Mental Health (ZI), University of Heidelberg, Germany) Günther´s journey into addiction research
10.30-10.50 Ilya Vinnikov (Molecular Neurobiology Lab, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China) RNA interference in mature melanocortinergic neurons protects from obesity
10:50-11:20 Coffee/Tea break
Session 6: Brain Health
Chair: François Tronche
11:20-11:40 Theo Mantamadiotis (The University of Melbourne, Australia) Tissue remodeling and cell signaling underpin heterogeneity in the glioma tumor microenvironment
11.40-12.00 Hai-Kun Liu (German Cancer Research Center (DKFZ), Germany) Next-generation human cancer modeling: Transforming cancer genetic heterogeneity into LEGO Blocks
12:00-12:20 Andrii Domanskyi (Orion Pharma Corporation, Turku, Finland) Targeting pathological protein aggregation in neurodegeneration: dead end or a new hope?
12.20-12.40 Grzegorz Kreiner (Dept. Brain Biochemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland) From TIF-IA to the pursuit of prodromal Parkinson’s disease model
12:40-13:00 Valerio Orlando (King Abdullah University of Science and Technology, Thuwal, Saudi Arabia) The RNA Repeatome: from junk to Therapeutics
Session 7: Industry and Society
Chair: Siegfried Ruppert
14:00-14:20 Setsuko Hashimoto (CellSeed Inc. Tokyo, Japan; Zoom – 20.30 Tokyo time) Bridging science to business
14:20-14:40 Erich Greiner (Cedrus Therapeutics, New York, USA) Günther co-founding a biotech company
14:40-15:00 Anton Bauer (4everProtein - INiTs, Vienna, Austria) Novel way to biological therapeutics
15:00-15:20 Thomas Lemberger (Scientific Publications, EMBO, Heidelberg, Germany) From bench to website
15:20- 15.40 Andreas Reik (Cell Therapy, Sangamo Therapeutics, Richmond, California, USA; via Zoom – 06.20 San Francisco time) Allogeneic to immunotherapy
16:00 Concluding remarks
18:30 Friday beer and dinner at Zum Roten Ochsen (Heidelberg, Old Town)
Saturday 21 May 2022
11:00 Boat ride to Neckarsteinach, then Biergarten or Hike, return by boat to Heidelberg
The Symposium will take place in a hybrid format.
Participants registering for the on-site symposium will be able to attend in Heidelberg, Germany at all sessions and supplementary program.
Directions can be found under the "How to find us" section in the upper left menu.
Participants registering for the virtual participation will only be able to attend the main sessions (via Zoom).
If you plan to attend the event online, please use the following Zoom information: