22–23 Jul 2026
Heidelberg Congress Center
Europe/Berlin timezone

Impact of telehealth exercise intervention on muscle strength, cardiorespiratory fitness, and quality of life in patients with cancer: a systematic review with meta-analysis

22 Jul 2026, 10:30
15m
Heidelberg Congress Center ( Heidelberg Congress Center )

Heidelberg Congress Center

Heidelberg Congress Center

Czernyring 20 69115 Heidelberg Germany
3 - Talk Oral Session

Speaker

Gloria Adamoli (Università di Verona)

Description

Introduction
Cardiorespiratory fitness (CRF), muscle strength are prognostic factors in cancer. Although exercise can improve these parameters, many patients remain insufficiently, especially due to the lack of accessible services. Telehealth interventions overcomes these obstacles, although concerns remains about its effectiveness. This meta-analysis primarily aims to determine the impact of exercise delivered via telehealth on CRF, strength, and quality of life (QoL) in patients with cancer.

Methods
A systematic search on PubMed/MEDLINE, Scopus, Web of Science, CINAHL, and Cochrane was conducted. Randomized controlled trials testing the impact of exercise delivered by telehealth on CRF, upper- and lower-limb strength, and QoL were included. To quantify the magnitude of change a random-effects meta-analysis was conducted.

Results
Twenty-eight studies were included, comprising 2,212 patients (mean age 56.6 ± 8.6 years; BMI 28.3 ± 5.1 kg/m²). The sample included individuals with breast, prostate, and various mixed cancer types, mostly diagnosed with stage I–III disease. Telehealth-delivered exercise produced significant improvements in CRF (SMD = 0,204; p = 0,0007) and lower-limb strength (SMD = 0,41; p = 0,016). No significant effects emerged for upper-limb strength (SMD = 0,01; p = 0,94), QoL (SMD = 0,09; p = 0,566), and physical function (SMD = 0,26; p = 0,134). Stratifying for telehealth mode, eHealth interventions showed greater benefits for CRF and lower limb strength, wearable device for CRF and gaming for physical functioning. About exercise type, aerobic training revealed larger improvements in CRF and combined interventions (aerobic + resistance) in CRF, lower-limb strength and physical functioning.

Conclusion
Telehealth-delivered exercise significantly improve CRF and lower-limb strength in patients with cancer, although effects on QoL and upper-limb strength remain limited. Overall, these findings support telehealth as a promising strategy to improve key fitness outcomes while underscoring the need for more targeted and standardized interventions.

Keywords

Telehealth
Exercise
Physical fitness
Quality of life

Abstract submitters declaration yes
Conflict of Interest & Ethical Approval yes

Authors

Gloria Adamoli (Università di Verona) Alice Barnini (Fondazione Policlinico Universitario A. Gemelli, IRCCS-Epidemiology & Biostatistic, Rome, Italy) Anita Borsati Francesco Bettariga (Exercise Medicine Research Institute. Edith Cowan University) Cristina Crespo-Garcia (Exercise Medicine Research Institute, Edith Cowan University, Perth, Australia) Arianna Giorgetti (Section of Oncology, Department of Engineering for Innovation Medicine (DIMI), University of Verona and Verona University Hospital Trust, Verona, Italy) Christian Ciurnelli (University of Verona) Robert Newton (Edith Cowan University) Michele Milella (University of Verona) Federico Schena (University of Verona) Diana Giannarelli (Fondazione Policlinico Universitario A. Gemelli, IRCCS-Epidemiology & Biostatistic, Rome, Italy) Sara Pilotto (Section of Innovation Biomedicine – Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Italy) Alice Avancini (University of Verona)

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