ISEO – Inaugural Conference July 22nd & 23rd 2026 - organized by DKFZ

Session

Oral Session 3

22 Jul 2026, 15:15

Description

Chairs: Karen Steindorf & Lene Thorsen

350. Patterns of physical activity and fatigue in patients receiving immunotherapy for melanoma

Sarah Marvin (Sydney School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia. Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia), Kate Edwards (Sydney School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia. Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia)

22/07/2026, 15:15

3 - Talk

Background: The efficacy of physical activity (PA) in managing fatigue has been well-established for a range of cancers and treatment types. However, whilst patients with melanoma commonly report fatigue as a side-effect of immunotherapy treatment, the relationship with physical activity is not well-understood in this population. This ongoing study aims to examine the relationship between PA...

193. Daily In-Hospital Exercise During Neoadjuvant Chemoradiotherapy Counteracts Immune Suppression in Patients With Esophageal Cancer

Anna Ubink (Department of Laboratory Medicine, Laboratory Medical Immunology, Radboud University Medical Centre, Nijmegen, the Netherlands; Department of Medical BioSciences, Radboud University Medical Centre, Nijmegen, the Netherlands)

22/07/2026, 15:30

3 - Talk

Background: In our previous study, exercise during neoadjuvant chemoradiotherapy (NCRT) showed potential to enhance tumor regression in patients with esophageal cancer, but underlying mechanisms are unclear. As preclinical evidence suggests that exercise decreases tumor growth through mobilization, activation, and tumor infiltration of natural killer (NK) and CD8+ T cells, we explored these...

278. Functional Reserve and Sarcopenia Shape Treatment Outcomes After CAR-T Cell Treatment: Results of a Real-World Pilot Study

Alessandra Holzem (Department of Medicine III, LMU Hospital Munich)

22/07/2026, 15:45

3 - Talk

Objective
Assessment of patient fitness before CAR-T cell therapy relies on the subjective ECOG performance status (PS), offering limited granularity for clinical decision-making. To establish a more objective reproducible evaluation, we implemented two standardized bedside physical performance tests. In this prospective pilot study, we investigated whether quantitative measures of functional...

134. Effect of adding exercise therapy to first-Line chemotherapy on progression-free survival and wellbeing in ovarian cancer: Results from the phase 3 ECHO trial

Sandra Hayes (Cancer Council Queenslnd)

22/07/2026, 16:00

3 - Talk

Introduction:
ECHO is a phase 3 randomised controlled trial designed to determine whether adding exercise therapy into first-line chemotherapy effects progression-free survival (PFS) and physical wellbeing in women newly diagnosed with ovarian, primary peritoneal, or fallopian tube cancer (ANZCTRN12614001311640).
Methods:
Participants were allocated to either standard chemotherapy plus...

126. The influence of exercise on the relationship between neuropathic pain and its interference with daily activities among cancer patients receiving chemotherapy

Po-Ju Lin (Wilmot Cancer Institute, University of Rochester Medical Center)

22/07/2026, 16:15

3 - Talk

Introduction. Chemotherapy-related neuropathic pain (i.e., hot/burning or sharp/shooting sensations) substantially interferes with cancer patients’ ability to perform daily activities. Exercise is a promising therapy that may reduce neuropathic pain and its interference with daily activities during chemotherapy.

Methods. We conducted a nationwide phase II randomized controlled trial through...