Description
Chairs: Karen Steindorf & Lene Thorsen
Background: The efficacy of physical activity (PA) in managing fatigue has been well-established for a range of cancers and treatment types. However, whilst patients with melanoma commonly report fatigue as a side-effect of immunotherapy treatment, the relationship with physical activity is not well-understood in this population. This ongoing study aims to examine the relationship between PA...
Background: In our previous study, exercise during neoadjuvant chemoradiotherapy (NCRT) showed potential to enhance tumor regression in patients with esophageal cancer, but underlying mechanisms are unclear. As preclinical evidence suggests that exercise decreases tumor growth through mobilization, activation, and tumor infiltration of natural killer (NK) and CD8+ T cells, we explored these...
Objective
Assessment of patient fitness before CAR-T cell therapy relies on the subjective ECOG performance status (PS), offering limited granularity for clinical decision-making. To establish a more objective reproducible evaluation, we implemented two standardized bedside physical performance tests. In this prospective pilot study, we investigated whether quantitative measures of functional...
Introduction:
ECHO is a phase 3 randomised controlled trial designed to determine whether adding exercise therapy into first-line chemotherapy effects progression-free survival (PFS) and physical wellbeing in women newly diagnosed with ovarian, primary peritoneal, or fallopian tube cancer (ANZCTRN12614001311640).
Methods:
Participants were allocated to either standard chemotherapy plus...
Introduction. Chemotherapy-related neuropathic pain (i.e., hot/burning or sharp/shooting sensations) substantially interferes with cancer patients’ ability to perform daily activities. Exercise is a promising therapy that may reduce neuropathic pain and its interference with daily activities during chemotherapy.
Methods. We conducted a nationwide phase II randomized controlled trial through...
