Description
Chairs: Karen Mustian & Bernd Alt-Epping
PURPOSE: Cancer related fatigue (CRF) is highly prevalent among individuals living with advanced cancer. Although cancer rehabilitation programs can reduce CRF over time (e.g., 8-12 weeks), the immediate or “acute” effect of exercise sessions on CRF is unclear. This study compared CRF from immediately before to after exercise sessions among individuals living with advanced cancer who were...
BACKGROUND: Patients with metastatic breast cancer (MBC) are often excluded from exercise research and programming, despite potential benefits. Given the unique needs and understudied relationship of this population with exercise, we sought to evaluate barriers to participation in supervised exercise for women with MBC.
METHODS: Eligible patients (n=60) had stable MBC, were not meeting...
Background:
Immune checkpoint inhibitors (ICIs) have become standard of care first-line therapy for patients with advanced renal cell carcinoma (aRCC). Although ICIs improve survival, treatment outcomes are limited due to primary and secondary resistance as well as immune-related adverse events (irAEs). Preclinical work suggests that exercise may enhance antitumor immunity, reduce...
Background: Exercise is an established supportive therapy in oncology, with growing interest in its role for individuals with incurable disease who commonly experience progressive functional decline. Resistance training is recommended in current guidelines, but its effectiveness and clinical translation depend on appropriate application and transparent reporting of key exercise principles...
PURPOSE: Preclinical evidence suggests that acute exercise can modulate immune responses and enhance tumor perfusion, potentially improving chemo-immunotherapy (ChemoIO) efficacy. The ERICA trial (NCT04676009) evaluated the feasibility, safety, and preliminary effects of acute aerobic exercise performed immediately prior to ChemoIO in patients with metastatic non-small cell lung...
Background
Patients with advanced colorectal cancer frequently present impairments in clinical parameters and physical function even before initiating chemotherapy, which raises concerns about their participation in an exercise training program. Baseline characterization is essential for designing individualized and feasible exercise interventions and understanding how initial physiological...
