ISEO – Inaugural Conference July 22nd & 23rd 2026 - organized by DKFZ

Session

Oral Session 5

Jul 23, 2026, 10:15 AM

Heidelberg Congress Center

Description

Chairs: Sandi Hayes & Andreas Schneeweiß

86. The randomized controlled BENEFIT trial investigating the effects of aerobic or resistance exercise concomitant to neoadjuvant chemotherapy on clinical outcomes in women with breast cancer

Martina Schmidt (Division of Physical Activity, Cancer Prevention and Survivorship, German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Heidelberg, a partnership between DKFZ and University Medical Center Heidelberg, Germany)

7/23/26, 10:15 AM

3 - Talk

Rationale: Preclinical and observational evidence suggests that exercise may enhance primary tumor treatment, but evidence from clinical trials is scarce. We therefore conducted a randomized controlled trial to examine the effects of adding exercise to neoadjuvant chemotherapy (NACT) on clinical outcomes.

Methods: In the BENEFIT trial, breast cancer patients scheduled for NACT were...

94. Improving sleep quality of patients with metastatic breast cancer through supervised exercise: results from the PREFERABLE-EFFECT trial

Jana Müller (Exercise Oncology Research Group, Department of Medical Oncology, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, National Center for Tumor Diseases Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany)

7/23/26, 10:30 AM

3 - Talk

Background: Impaired sleep quality is a common burden in patients with breast cancer, yet the effects of exercise on sleep quality, particularly in patients with metastatic disease (mBC), remain understudied. Therefore, the effects of supervised exercise on sleep quality in patients with mBC were investigated in the multinational randomized controlled PREFERABLE-EFFECT...

65. Exploring the feasibility of exercise training during (neo)adjuvant chemotherapy in women with early-stage breast cancer: a pilot study examining immune and metabolic outcomes

Cristina Crespo García (Exercise Medicine Research Institute. Edith Cowan University)

7/23/26, 10:45 AM

3 - Talk

Background:
Immune function critically influences chemotherapy efficacy. Preclinical evidence is that exercise mobilizes NK and CD8+ T cells, enhances immunosurveillance, and improves treatment response. However, its immunological effects during chemotherapy for breast cancer remain poorly defined.
Methods:
This non-randomized pilot study examined a 12-week supervised combined aerobic-...

258. Exercise during chemotherapy for breast cancer: Not just improving patients’ functional ability

Argyro Papadopetraki (Physiology Laboratory, Medical School, National and Kapodistrian University of Athens)

7/23/26, 11:00 AM

3 - Talk

Background: Exercise during chemotherapy for breast cancer (BCa) offers significant health benefits and could influence disease progression. Evidence suggests that exercise-induced circulating factors mediate such anticarcinogenic effects, although the implicated cellular processes remain uncharacterized.

Method: Twenty-nine BCa patients (40.0±0.9 yrs, 25.0±0.8 kg/m2) were randomized with...

74. Habitual physical activity patterns and longitudinal changes in insulin resistance following breast cancer diagnosis and treatment

Richard Viskochil (Department of Exercise and Health Science, University of Massachusetts Boston)

7/23/26, 11:15 AM

3 - Talk

PURPOSE: Insulin resistance (IR) and hyperglycemia are common side effects of cancer therapy, and IR that persists despite treatment cessation is likely much more common than previously estimated. It is unclear if habitual physical activity (PA) alters cancer-induced IR in the year after diagnosis. METHODS: Fasting glucose, insulin, and self-reported PA were measured at diagnosis, 6-, and...