Background: Hormone receptor-positive breast cancer patients receiving aromatase inhibitor (AI) therapy commonly experience adverse effects such as joint pain, fatigue, and reduced quality of life. These symptoms can affect treatment adherence and survivorship. Given the growing number of breast cancer survivors, understanding supportive care strategies such as exercise is critical for...
Background: Head and neck cancer (HNC) and its treatments have significant detrimental effects on multiple survivorship domains. Multimodal programs incorporating exercise-based interventions are frequently integrated as supportive care strategies in western cohorts, however evidence in resource constrained settings remains scarce. The purpose of this study was to evaluate the effects of...
Background: Psychological symptoms, including anxiety and depression are prevalent among patients living with and beyond cancer. Limited research suggests that exercise effects might differ between patients with low or elevated symptoms of anxiety or depression. However, single randomized controlled trials (RCTs) are often underpowered to detect moderation effects. Hence, drawing on...
Background: Although exercise therapy has the potential to address physical decline, symptoms, and reduced quality of life (QOL) in patients with bone metastases, its effectiveness has not been sufficiently examined. This scoping review aimed to identify, summarize and map the relevant literature that provides information on the effects of exercise on physical function, symptoms, and QOL in...
Background: Cancer-related fatigue (CRF) is one of the most distressing symptoms experienced by individuals with cancer and significantly affects physical functioning and quality of life. Although exercise is recognized as an effective strategy for managing CRF, racialized women remain underrepresented in exercise oncology research. This systematic review synthesized evidence from randomized...
Background
Tumor-infiltrating lymphocyte (TIL) therapy is an intensive adoptive T-cell treatment for meta-static malignant melanoma (MM) that can induce sustained clinical responses in patients with advanced disease, including after failure of immune checkpoint inhibitors. The treatment in-volves tumor excision, ex vivo TIL expansion (5–7 weeks), lymphodepleting chemotherapy, and high-dose...
Purpose-Latina/Hispanic breast cancer survivors (LHBCS) often experience worse outcomes due to late diagnosis, poor treatment adherence, and limited healthcare access. LHBCS also show insufficient physical activity levels, which may contribute to poorer treatment outcomes. Low income, limited education, and restricted healthcare access strongly influence cancer screening and survival....
Category: Survivorship or Remote/Digital Integration
Background:
Cancer-related fatigue (CRF) is one of the most prevalent and persistent symptoms among cancer survivors, significantly impacting quality of life and functional participation. Exercise is an evidence-based intervention for CRF; however, many survivors remain exercise-naïve and require structured support when initiating exercise...
Background:
Chemotherapy-induced peripheral neuropathy (CIPN) is a side effect of the administration of oxaliplatin, a neurotoxic agent, which causes dysfunction of peripheral neurons and interferes with quality of life. Pharmacological therapies have shown limited efficacy in controlling symptoms, leading to the exploration of physical exercise as a therapeutic alternative....
Diagnosed with breast cancer during the pandemic of COVD-19, professional ballet dancer and professor with 43 years old had a mastectomy with reconstruction, followed by hormonal treatment (Tamoxifen). Patient had family breast cancer history (mother twice-35y/75y; cousins, greatgrandmother and grandmother’s sister). Before diagnosis patient was a high performance athlete with professional...
Introduction: Breast cancer and obesity have been independently associated with functional limitations and reduced quality of life (QoL). However, the extent to which physical activity modifies obesity-related impairments in breast cancer survivorship remains unclear. This study aimed to compare functional performance and QoL across groups defined by obesity status and physical activity level...
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of neurotoxic chemotherapy that can affect functioning and quality of life. No effective pharmacological treatments exist, highlighting the need to understand non-pharmacological strategies such as exercise. Given significant heterogeneity in the CIPN outcome measures chosen across studies, this scoping review aimed to...
Background
Exercise oncology programs demonstrate short-term benefits for physical function and quality of life (QOL); however, evidence supporting long-term survivorship outcomes remains limited.
Purpose
To describe five-year survivorship health status, physical activity (PA), and QOL among participants who completed 12-week in-person exercise programming for the Alberta Cancer...
Purpose
To examine the associations between baseline sleep quality and patient-reported outcomes (PROs) during neoadjuvant breast cancer (BC) treatment, and whether participation in an exercise program modified these associations.
Methods
Women undergoing neoadjuvant BC treatment participated in supervised exercise or usual care as part of the Neoadjuvant Exercise Oncology Program...
Background: Cognitive impairment, including memory and attention problems (“chemo-brain”), following chemotherapy is present in as many as 70% of patients treated with chemotherapy. High-intensity Interval Training (HIIT) has shown to be more effective than moderate continuous intensity aerobic exercise for improving cognitive function among adults. Therefore, the CLARITY Trial sought to...
Background
Exercise is increasingly recognized as beneficial in addressing breast cancer treatment-related sequelae including lymphedema. However, uncertainty remains regarding the safety of low levels of supervision. Currently, only supervised exercise is recommended for those at risk of, or with, lymphedema, yet head-to-head trials directly comparing supervision levels are limited. These...
Background: Despite survival gains with immune checkpoint and targeted therapies, toxicities and adverse effects—particularly fatigue—impair quality of life in melanoma patients. Although exercise benefits are established in oncology, its integration in melanoma care is underexplored. RESPECT examines whether a supervised hybrid (online/in-person) exercise program reduces fatigue and improves...
Background: Cancer often brings psychological challenges such as distress, depression, and anxiety, which can negatively affect health outcomes. Exercise is known to improve these symptoms, yet the mechanisms underlying its psychological benefits remain unclear.
Aims: This feasibility study examined the effect of a six-week resistance training programme on exercise-self-efficacy,...
Purpose: Deep Inspiration Breath Hold (DIBH) is an established technique to reduce cardiac dose in left-sided breast radiotherapy. Successful implementation requires adequate thoracic expansion, stable plateaus, and sufficient apnea-time. This study evaluates the effect of structured respiratory training on breath-hold performance and DIBH eligibility, and whether breath-hold capacity mediates...
Introduction: Physical activity during treatment for cancer has been shown to improve function, and reduce treatment-related side effects, but existing evidence is largely derived from early-stage and more common cancers and may not reflect the experiences of women with ovarian cancer. This qualitative study explored side effects associated with chemotherapy and experiences with physical...
Current evidence suggests that exercise is safe and well-tolerated by cancer patients and has potential to mitigate cancer-related fatigue (CRF), a distressing and undermanaged adverse event. This study evaluated if supervised group exercise for 60 minutes (aerobic/strength), 2-3 times/week for 12 weeks, can impact CRF over time. FACIT-FS, a self-reported questionnaire, was used to assess CRF...
Context Cancer-related fatigue (CRF) is one of the most prevalent and debilitating symptoms among cancer survivors. Although physical activity is widely recommended to mitigate CRF, existing evidence largely relies on retrospective, between-person approaches that fail to capture intra-individual fluctuations and contextual influences in daily life. Ambulatory Assessment (AA) enables...
Background/Purpose: Cancer-related fatigue (CRF) is a common, debilitating symptom among cancer survivors. Exercise-based cancer rehabilitation improves CRF over time but less is known about acute effects. This study examined week-to-week changes in CRF from before to after exercise sessions during a 12-week outpatient rehabilitation program.
Methods: As part of an observational,...
Introduction: Cancer survivors experience many symptoms years after treatment. This overall symptom burden interferes significantly with the ability to work and perform activities of daily living (ADLs). Yoga, a form of exercise, is a promising therapy to mitigate these symptoms.
Methods: We conducted a nationwide, multicenter, phase III, RCT testing the effect of Yoga for Cancer Survivors...
