Purpose
Lung, breast, and bowel cancers account for ~40% of new UK cancers and 38% of cancer-related deaths. Despite advances in diagnosis and treatment, an urgent unmet need to improve recovery from cancer treatments remains. Evidence suggests a 38% risk reduction in breast and bowel cancer-specific mortality with exercise, yet most is observational. More clinical trials are needed to build...
Pelvic floor symptoms following robotic-assisted laparoscopic prostatectomy (RALP) can reduce participation in meaningful activities, including exercise. Although pelvic floor physical therapy is becoming a standard intervention for post-prostatectomy patients with symptoms like stress urinary incontinence (SUI), there is limited guidance to safely progress patients into higher-impact...
Background: Advanced prostate cancer is frequently associated with bone metastases and a decline in skeletal muscle mass (SMM), with the latter partly attributable to androgen deprivation therapy (ADT). Although higher SMM has been linked to improved quality of life (QoL), resistance training at high loads is often not feasible in patients lacking an anabolic androgen stimulus. Blood flow...
Background: Understanding the motivational effects of exercise during or after intravesical therapy for non-muscle invasive bladder cancer (NMIBC) may help patients to initiate and sustain exercise behavior. We report the effects of exercise on motivational outcomes, perceived benefits and harms, and perceived barriers to exercise during or after NMIBC intravesical therapy. Methods: NMIBC...
Introduction: Optimizing exercise training through periodization is important for improving strength and aerobic performance (Boggenpoel, Nel, & Hanekom, 2018; Soares et al., 2022). In this context, periodized exercise training is also considered an effective method for improving psychosocial parameters such as health-related quality of life. However, there are no studies in the field of...
Background: About one-third of cancer patients participate in a unique three-week rehabilitation program after tumor treatment in Germany. Given the short duration, therapy must be highly efficient, yet exercise prescription is often not individualized.
Methods: In this randomized controlled trial, we compared two exercise arms. The individualized training arm (IT) trained at 50% of...
Background: It is widely recognized that exercise reduces the risk of cancer and disease recurrence. Yet the mechanisms behind these benefits remain to be elucidated. We previously showed that voluntary wheel running in tumor-bearing mice reduced tumor incidence and growth by more than 60% across different tumor models. Moreover, this effect was mediated via exercise-associated increases in...
Background:
Chimeric Antigen Receptor T-cell (CAR-T) therapy is an advanced treatment for hematologic malignancies, often associated with significant physical deconditioning, functional decline, and long-term complications. Evidence regarding rehabilitation following CAR-T remains limited.
Case Presentation:
A 26-year-old woman with relapsed disease underwent multiple chemotherapy...
Background
One in five patients with cancer in the Netherlands has a rare cancer, affecting approximately 20.000 new people per year. However, there is a lack of research on supportive cancer care in this population, resulting in a lack of knowledge on quality of life optimalization.
It is unclear if the beneficial effects of exercise in patients with common cancers can be generalized...
Introduction: Exercise in patients undergoing anticancer treatments is recognized for attenuating side effects, improving symptoms, and enhancing quality of life (QoL). However, its implementation in real-world settings remains limited. This study assessed the feasibility and the impact of a structured EX program in patients receiving anticancer therapies on physical fitness and QoL.
Methods:...
Background: Androgen deprivation therapy (ADT) for intermediate and high-risk prostate cancer (PC) improves survival but leads to negative changes in body composition, muscular strength, and physical fitness that compromises quality of life (QOL) and places men at risk of secondary commorbidities.
Methods: Twenty-seven medically underserved men (≥75 years of age, and/or Black,...
Background: Oncological patients experience numerous side effects resulting from disease and treatment. Although exercise is recommended, many side effects and patients’ concerns hamper its regular implementation. Especially patients with reduced physical function are often not able to exercise with the necessary intensity to increase muscle mass. An innovative training approach uses lower...
Background: Exercise interventions are consistently evidenced as effective supportive therapy measures in oncology. Meta-analyses and clincial guidelies demonstrate beneficial effects in quality of life, physical function, cardiorespiratory fitness, and improvements in treatment-related adverse effects through resistance and aerobic training. However, individual studies report substantial...
Background:
Major liver resections are associated with high postoperative complication rates, reported in up to 43% of cases. Prehabilitation programs that improve preoperative aerobic fitness enhance postoperative outcomes, yet the metabolic demands during recovery remain unclear. Insight into postoperative energy expenditure relative to preoperative metabolism and aerobic capacity is...
Background
This case study presents the multidisciplinary clinical management of an 82-year-old colorectal cancer patient through three surgeries. The Clinical Exercise Physiologist runs the General Practitioner (GP) exercise referral scheme and the cancer prehabilitation and rehabilitation service with University Hospital Southampton NHS Foundation Trust.
Case Presentation
All...
Introduction: Cancer-related fatigue (CRF) is common amongst breast cancer survivors, severely affecting quality of life (QoL) after treatment. Although targeted exercise, such as aerobic or strength training, appear to be helpful, the optimal type and exercise parameters require further investigation. These case series explored the effects of a fast-track individually tailored combined...
Purpose
Blood-flow restricted resistance training (BFR-T), which uses low loads, may reduce mechanical stress and support faster muscle recovery compared with heavy-load training. Delivered at home, it may also improve exercise accessibility for cancer survivors, yet limited research has explored their experiences. This study aimed to qualitatively examine participants’ perspectives of a...
Background: Cardiovascular diseases are the second leading cause for increased morbidity and mortality in cancer survivors. With ongoing advances in surgical and adjuvant cancer therapies, an increasing number of survivors are living longer and require targeted support to manage long-term cardiovascular risk factors.
Methods: This secondary subgroup analysis includes participants who...
