Background: Older adults with cancer and reduced functional capacity face barriers to maintaining physical activity during treatment. This study describes the feasibility and preliminary effects of a 12-week telehealth-based exercise program in adults ≥65 years with cancer and instrumental activities of daily living (IADL) scores <70, indicating functional vulnerability.
Methods: We...
Background: With colorectal cancer ranking third globally and survival rates increasing, managing long-term complications is crucial. Most patients who undergo Patients undergoing Low Anterior Resection (LAR) often suffer from symptoms such as constipation, fecal incontinence, and urgency, which significantly compromise their quality of life. Although effective exercise interventions exist,...
Background:
Mind-body interventions such as yoga are increasingly recognized as integral components of supportive cancer care. Yoga, combining strengthening mindful movements, breathing, and relaxation techniques, has demonstrated positive effects on common cancer side effects such as cancer-related fatigue (CRF) and emotional distress. However, heterogeneity of patient needs, physical...
Background and objective: With rising cancer incidence, also the number of patients receiving chemotherapy and experiencing treatment-related side effects is increasing. While robust evidence shows that exercise during treatment yields beneficial effects in the attenuation of these side effects, exercise participation and adherence during chemotherapy remain critically low. Therefore, the...
Introduction: Reporting exercise compliance within intervention trials is critical to establish realistic expectations and inform best practices for cancer survivors. This secondary analysis describes compliance to a virtually supervised, home-based 16-week aerobic and resistance exercise intervention among Latina/Hispanic breast cancer survivors (LHBCS).
Methods: This analysis includes 26...
Introduction
Active Together is a clinician-led cancer prehabilitation and rehabilitation service for adults with cancer receiving curative treatment that is embedded into NHS cancer care pathways across South Yorkshire, UK. This real-world service evaluation assessed the feasibility, engagement, and impact of this multimodal service combining exercise, dietetic, and psychological support...
Background
Cancer prehabilitation which aims to optimize physical fitness before treatment can enhance patient resilience. With increasing digitalization in healthcare, digital cancer prehabilitation has emerged as a promising approach to overcome accessibility and implementation barriers of traditional prehabilitation programs. However, the concept remains inconsistently defined across the...
Background: People living with and beyond cancer experience multiple health challenges. Although physical activity (PA) reduces the most common side effects and successfully improves quality of life, PA levels among this population remain low due to limited support and low self-efficacy. Many survivors seek PA-related information through digital health resources, such as websites, documents,...
Background
Cancer prehabilitation (prehab) includes exercise, nutritional optimisation, and support for emotional wellbeing, before cancer treatment. Despite demonstrated benefits for recovery, access to and engagement with cancer prehab remain inequitable, particularly among people from minority ethnic backgrounds and socioeconomically disadvantaged communities. To address this, we...
Purpose The recent surge in live-remote exercise programs may facilitate greater access to exercise interventions for cancer survivors. However, concerns have been raised about altered or weakened interpersonal dynamics among participants and between participants and exercise professionals. This could affect perceived benefits and subsequent opportunity for survivors to play an active role...
Background:
Depression and anxiety are common among women with cancer and negatively affect treatment, recovery, and quality of life. Accessible, home-based interventions are needed to address these symptoms.
Purpose:
To evaluate the feasibility, acceptability, and preliminary efficacy of a 6-week online yoga program delivered in either group or individual format for women with breast or...
Background: Cancer cachexia is a debilitating syndrome in advanced cancer, characterized by reduced physical function, high symptom burden, poor quality of life (QOL), and shortened survival. Despite the prevalence of cancer cachexia, supportive care options remain limited. Exercise is recommended in oncology, yet few trials have specifically targeted patients with advanced cancer and...
Background
Despite strong evidence supporting exercise during chemotherapy, access to supervised programs remains limited in regional settings due to workforce and service delivery constraints. Scalable models that maintain safety, fidelity, and clinical effectiveness across diverse healthcare contexts are urgently needed.
Purpose
To evaluate the feasibility, safety, and...
Background:
Exercise is one of the most evidence-based interventions in cancer care, shown to improve treatment tolerance, physical function, symptom burden and quality of life across the cancer continuum. Despite strong international guidelines, exercise remains inconsistently integrated into routine oncology care, with many services struggling to translate evidence into sustainable clinical...
Objectives/purpose
Intra-infusion exercise (i.e. exercise delivered during chemotherapy infusion) is a novel strategy to integrate exercise into cancer treatment. The EX-FUSION RCT evaluated the feasibility and efficacy of this approach. This qualitative study explored healthcare professionals (HCPs) experiences delivering the EX-FUSION intervention and their recommendations on future program...
Background
Prehabilitation for patients awaiting cancer treatment comprises support for exercise, nutrition, and emotional well-being. Prehabilitation is associated with faster recovery and improved outcomes. However, practical action to improve inclusion in prehabilitation is needed to reduce inequities in cancer care and outcomes. This study explored prehabilitation practices within cancer...
Background: Physical activity is essential for improving outcomes and managing side effects in cancer patients. App-based exercise interventions may enhance access to exercise therapy. To provide precise recommendations, accurate assessment of physical function and limitations is crucial. This feasibility study investigated a digitally assisted exercise program and the role of comprehensive...
There is a strengthening mandate from the literature, clinical bodies’, clinician experience and the patient voice adding weight to the argument that physical activity should be a standard component of cancer care. What is less clear is how this is implementable in over stretched clinical settings where priorities are significantly influenced by funding and exercise healthcare professionals do...
Regular physical activity plays a critical role in improving health outcomes and quality of life for individuals affected by cancer. This poster presents the work of a non-profit organization that has been providing free exercise classes for the past 19 years to individuals impacted by cancer, including those in active treatment, survivorship, and recovery.
To date, the program has...
Background: With prehabilitation’s inclusion in the 2026 NHS National Cancer Plan, understanding barriers and facilitators to cancer prehabilitation from an individual to a systems level is vital to scale services. Since 2021, the Cancer Treatment Outcomes Programme (CTOP) has delivered high-quality multimodal prehabilitation across County Durham and Darlington, a rural and deprived community...
Background:
The Neo-ACT trial is an ongoing, pragmatic RCT evaluating whether structured, home-based exercise during neoadjuvant chemotherapy can improve treatment efficacy in patients with breast cancer. The enrolment target is 712 evaluable participants; as of December 2025, 339 participants have been randomized. The intervention consists of 120 minutes of weekly exercise combining...
Purpose: Exercise is an evidence-based, effective therapy for breast cancer survivors, relieving treatment side effects (e.g., fatigue, depression), improving quality of life, and possibly extending survival. Geographical barriers create disparities in access to cancer exercise programs. For many breast cancer survivors, accessing an in-person exercise program is a logistical challenge due...
Background
Long-term adherence remains one of the main challenges in exercise oncology. To address this, the PRIME Center IOR (Cesena, Italy) operates as a multidisciplinary oncology rehabilitation facility integrating physiotherapy and supervised exercise delivered by oncology-trained professionals. However, longitudinal real-world data describing adherence patterns across different...
BACKGROUND: Older adults with cancer are up to 2.5 times more likely to have functional decline and 4 times more likely to be frail compared to older adults without a cancer history or cancer survivors. Exercise is one of the most effective and evidence-based strategies to improve several functional and psychological outcomes and demonstrates elevated benefits on disease-free and overall...
