Description
Chairs: Eva Zopf & Scher Mama
Background:
The multinational PREFERABLE-EFFECT RCT (NCT04120298) demonstrated beneficial effects of a 9-month supervised exercise program on fatigue and quality of life among patients with metastatic breast cancer (mBC). As a secondary outcome of the study, we investigated the impact of the exercise program (2x/week resistance, aerobic and balance training) on systemic inflammation and...
Physical activity induces rapid, selective leukocyte mobilization, thereby modulating immune surveillance. Among the most responsive cell types to high-intensity exercise are NK and CD8+ T cells, key effectors of immune defense against infected and malignant cells. However, comprehensive characterization of acute high-intensity interval training (HIIT)-induced effects on leukocyte populations...
Purpose. We investigated the impact of training status (untrained versus trained) on acute myokines with anti-cancer properties and cancer cell suppression before (untrained) and after (trained) a 12-week resistance training (RT) vs high-intensity interval training (HIIT) program.
Methods. Twenty-eight breast cancer survivors completed a single bout (defined as one complete exercise session)...
Introduction:
Numerous studies have reported exercise-induced changes in circulating factors that may partly explain the association between physical activity and reduced cancer risk (1, 2). Acute exercise-conditioned serum from both healthy individuals and patients has been shown to reduce the viability of several cancer cell lines, suggesting that transient changes in soluble factors such...
Background: Colorectal cancer and its treatments accelerate declines in skeletal muscle health, decreasing physical function and increasing vulnerability to morbidity and mortality. While resistance exercise training (RET) is recommended to counter these declines, individuals with cancer may experience a blunted adaptive response. Further, to date RET’s impact on skeletal muscle ultrastructure...
INTRODUCTION
It has been suggested that exercise during chemotherapy drug infusions might be beneficial for cancer patients. The rationale is that pre-clinical studies have shown increased tumor blood flow during exercise, which could enhance drug delivery into the tumor. However, this phenomenon remains sparsely investigated in the clinical setting in cancer patients and was therefore the...
