ISEO – Inaugural Conference July 22nd & 23rd 2026 - organized by DKFZ

Session

Thematic Poster Session 2

22 Jul 2026, 12:15

Heidelberg Congress Center

Description

Chairs: Eva Zopf & Scher Mama

250. Exercise training reshapes the systemic immune environment in patients with metastatic breast cancer: results from the PREFERABLE-EFFECT multi-centre randomised-controlled trial

Elisa Heyrman (Division of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden & Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden)

22/07/2026, 12:15

1 - Scientific Poster

Background:
The multinational PREFERABLE-EFFECT RCT (NCT04120298) demonstrated beneficial effects of a 9-month supervised exercise program on fatigue and quality of life among patients with metastatic breast cancer (mBC). As a secondary outcome of the study, we investigated the impact of the exercise program (2x/week resistance, aerobic and balance training) on systemic inflammation and...

101. Acute HIIT preferentially mobilizes virus-reactive CD8+ T cells and enhances leukocyte migratory capacity

Katharina Leuchte (National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital Herlev)

22/07/2026, 12:20

1 - Scientific Poster

Physical activity induces rapid, selective leukocyte mobilization, thereby modulating immune surveillance. Among the most responsive cell types to high-intensity exercise are NK and CD8+ T cells, key effectors of immune defense against infected and malignant cells. However, comprehensive characterization of acute high-intensity interval training (HIIT)-induced effects on leukocyte populations...

357. Does Training Status Influence Myokine Levels and Cancer Cell Suppression In Vitro? Effects of a Single Bout of Exercise in Breast Cancer Survivors

Francesco Bettariga (University of Technology Sydney)

22/07/2026, 12:25

4 - Thematic Poster Session

Purpose. We investigated the impact of training status (untrained versus trained) on acute myokines with anti-cancer properties and cancer cell suppression before (untrained) and after (trained) a 12-week resistance training (RT) vs high-intensity interval training (HIIT) program.
Methods. Twenty-eight breast cancer survivors completed a single bout (defined as one complete exercise session)...

279. High-Intensity Exercise Serum Alters Glycolytic Metabolism and Proliferation Rate of A549 Lung Cancer Cells

Carlos Soares (CIPER, University of Coimbra, Portugal), Prof. Ana Teixeira (CIPER, University of Coimbra, Portugal)

22/07/2026, 12:30

1 - Scientific Poster

Introduction:
Numerous studies have reported exercise-induced changes in circulating factors that may partly explain the association between physical activity and reduced cancer risk (1, 2). Acute exercise-conditioned serum from both healthy individuals and patients has been shown to reduce the viability of several cancer cell lines, suggesting that transient changes in soluble factors such...

338. Ultrastructural Skeletal Muscle Adaptations to Resistance Exercise With or Without Creatine Supplementation in Individuals Treated for Colorectal Cancer

Thomas Cardaci (Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, USA)

22/07/2026, 12:35

1 - Scientific Poster

Background: Colorectal cancer and its treatments accelerate declines in skeletal muscle health, decreasing physical function and increasing vulnerability to morbidity and mortality. While resistance exercise training (RET) is recommended to counter these declines, individuals with cancer may experience a blunted adaptive response. Further, to date RET’s impact on skeletal muscle ultrastructure...

253. Tumor blood flow at rest and during exercise in breast cancer patients

Ilkka Heinonen (Turku PET Centre, University of Turku)

22/07/2026, 12:40

1 - Scientific Poster

INTRODUCTION
It has been suggested that exercise during chemotherapy drug infusions might be beneficial for cancer patients. The rationale is that pre-clinical studies have shown increased tumor blood flow during exercise, which could enhance drug delivery into the tumor. However, this phenomenon remains sparsely investigated in the clinical setting in cancer patients and was therefore the...