Background: Evidence shows that obesity and physical inactivity increase breast cancer (BC) risk among postmenopausal women and may also influence prognosis. Evidence from well-designed clinical trials remain insufficient. This study helps fill this gap by evaluating an intervention combining diet and exercise.
Objectives: The primary aim is to assess the effect of the intervention on cancer...
Purpose: To present a cross-sectional investigation analyzing the associations of whole-body phase angle (PhA) with sleep quality, fatigue, and global health in women newly diagnosed with breast cancer.
Methods: Sixty-four newly diagnosed breast cancer patients waiting for their first chemotherapy cycle were enrolled in this investigation [mean age, 52.0±9.5 years; body mass index (BMI),...
Background: Increasing physical activity levels during chemotherapy is crucial for health maintenance; however, adherence is difficult. We piloted a randomized controlled exercise intervention during chemotherapy for breast cancer. This abstract reports on recruitment, intervention adherence, and attrition.
Methods: The PROTECT Trial was a pilot randomized control trial studying...
Background: Breast cancer survivors (BCS) undergoing endocrine therapy often experience pain, anxiety, and depressive symptoms. Although exercise has been shown to reduce these effects, there is still limited evidence on whether its benefits vary according to endocrine therapy type. Purpose: To analyze the effects of 24 weeks of Mat Pilates on pain severity, pain interference, anxiety, and...
Chemotherapy is one of the main treatments for breast cancer. Cardiotoxicity can occur as a side effect of some of its components. On the other hand, regular physical exercise can improve overall and cardiovascular health of cancer patients. However, regarding cardiovascular health, most healthcare professionals still recommend exercises that predominantly involve aerobic metabolism....
Background: Patients with localized breast cancer receiving (neo)adjuvant chemotherapy often experience sleep disturbances, especially insomnia, which significantly impacts quality of life. This study primarily aimed to evaluate the effects of a 12-week exercise program on insomnia, with secondary outcomes on sleep quality, anxiety/depression, fatigue, pain, and exercise...
Despite its clinical effectiveness, radiation therapy (RT) is associated with multiple adverse effects that can impair functional capacity and overall recovery in individuals undergoing breast cancer (BC) treatment. Exercise has emerged as an evidence-based adjunctive approach to mitigate treatment-related toxicity and enhance musculoskeletal performance. This study aimed to examine the...
Background: Gynecologic cancer (GC) survivors frequently experience declines in quality of life (QoL), physical function, and body composition following treatment. Exercise has emerged as a key survivorship strategy. However, previous meta-analyses in this population have shown inconsistent findings and limited coverage of functional and anthropometric outcomes. This systematic review and...
Background: Women breast cancer survivors (WBCS) frequently present long-term impairments in cardiorespiratory fitness and functional capacity, which may negatively affect health outcomes and quality of life. Cardiopulmonary exercise testing (CPET) allows an integrative assessment of cardiovascular and metabolic function, while functional tests provide clinically meaningful indicators of...
Background: Breast cancer is the most prevalent cancer in South Africa with an incidence rate of 31.4 per 100,000 women, with 57.1% of cases reported at advanced stages (1)(2). Since 2009, numerous international studies have demonstrated the benefits of exercise in managing upper-arm lymphedema(3)(4)(5)(6). The executive committee of lymphology 2016 consensus document stated the need for a...
Background: Exercise during cancer treatment can reduce symptom burden over time, but the immediate effects of single exercise sessions are unclear. This study examined immediate changes in treatment-related side effects ─ fatigue, nausea, dizziness, pain, and mood ─ following exercise in patients with breast cancer undergoing neoadjuvant chemotherapy (NACT).
Methods: In this study,...
Purpose: Breast cancer survivors undergoing hormonal therapy with aromatase inhibitors face a significantly increased risk of developing musculoskeletal pain, leading to treatment discontinuation, greater risk of unemployment and other negative outcomes on their quality of life. While physical activity is a known strategy for symptom management, the comparative efficacy of different...
Cancer is affecting more and more people around the world. Among the different types of cancer, breast cancer is the one with the highest incidence worldwide, especially over 50 years. According to the National Cancer Institute (INCA), the estimated number of new cases in Brazil from 2023 to 2025 is 73,610 cases. One of the most important causes in the literature for the emergence of breast...
Cancer-related fatigue (CRF) is a prevalent and debilitating symptom experienced by breast cancer survivors, significantly impairing quality of life (QoL). CRF treatment requires a comprehensive approach due to its multifactorial nature. Exercise is an effective treatment for CRF, but it is unclear how socioeconomic status (SES) influences survivors’ participation and retention in exercise...
Introduction
DIEP flap reconstruction involves harvesting abdominal skin, adipose tissue, and perforating blood vessels to reconstruct one or both breasts following mastectomy. The procedure requires extensive abdominal wall dissection, affecting trunk muscle function, shoulder mobility, and posture, often leading to difficulty standing upright and shoulder impingement. Despite the complexity...
Background: Exercise is an effective measure for mitigating treatment-related side effects and improving physical functioning in cancer patients (Campbell et al., 2019), but not all patients benefit equally from exercise. Most research in exercise oncology has not sufficiently emphasized this inter-individual variability or explored the factors that may influence it. Goal of this study is to...
Background & Aim: Breast cancer related lymphedema (BCRL) is a chronic sequel affecting the psychosocial aspects of life in breast cancer survivors. Self-management in breast cancer requires active participation by the survivor in recuperation and rehabilitation, thus minimising treatment consequences and promoting health and well-being. Although awareness of BCRL is constantly monitored for...
Background. Chemotherapy entails some side effects that may hinder functional performance of women diagnosed with breast cancer (BC), which may result in low exercise levels. Although evidence consistently show favorable effects of exercise on BC, more information on recruitment and adherence rates in the neoadjuvant phase is needed.
Purpose. We describe real-world numbers for the...
Breast cancer treatment frequently leads to postoperative arm morbidity, including shoulder dysfunction, pain, reduced range of motion, seroma, and lymphedema. Despite this burden, many women at highest risk do not receive timely rehabilitation, resulting in preventable functional decline. To address this critical gap, we developed the Arm Morbidity following Breast Cancer Treatment (ARM-BCT)...
Background:
Breast cancer survivors (BCS) often experience impaired quality of life (QoL) due to treatment-related side effects, sedentary behaviour and suboptimal diet. The Movement and Health Beyond Care (MoviS) trial (NCT04818359) investigates lifestyle interventions combining psychological counselling, aerobic exercise and Mediterranean diet (MD).
Methods:
A total of 139 sedentary...
Background
Up to 95% of women undergoing adjuvant therapy for breast cancer experience cancer-related fatigue (CRF), which may persist beyond treatment and substantially impair quality of life. CRF is characterized by persistent fatigue that is disproportionate to activity level and not relieved by rest. Resistance training has shown beneficial effects on CRF; however, adherence during active...
Background
One in three breast cancer survivors develops cognitive complaints after chemotherapy. Physical exercise is a promising non-pharmacological treatment option for these complaints. The Physical Activity and Memory (PAM) study showed that physical exercise positively affects self-reported cognition. To get insight into underlying mechanisms, the role of biological markers needs to be...
Purpose: Breast cancer (BC) is the most prevalent malignancy among women worldwide, with continuously improving survival rates. Increasing evidence supports the role of physical activity (PA) in reducing the risk of recurrence and mitigating modifiable risk factors such as obesity and sedentary behavior. However, promoting PA remains challenging, particularly in patients with comorbidities....
Background: This randomized controlled trial (RCT) examined the short-term effects of a phase-tailored, home-based exercise program for women with stage I–III breast cancer. The aim was to evaluate whether the intervention improves metabolic biomarkers and postoperative shoulder function (strength and range of motion, ROM) during the first 6 months after surgery.
Methods: In this...
